Tue04Feb20204:00 pmLewis Hall 101
Colloquium: Patterned Nanoscale Magnetic Traps and Applications for Single- and Few-Molecule Experiments
Department of Physics
Patterned Nanoscale Magnetic Traps and Applications for Single- and Few-Molecule Experiments
Directed and controllable manipulation of fluid-borne entities is important for a wide range of applications such as cellular diagnostics and nano-scale assembly. We present a multiplexed mechanism for manipulating microscopic magnetic particles in fluid on arrays of patterned magnetic disks or wires. This mechanism allows for probing and manipulation of micro- and nano-scale objects and biological entities in near-native environments, offers the flexibility to apply forces to large numbers of objects simultaneously, and is remotely tunable by application of weak magnetic fields. We illustrate several applications of this technique in the regime of single or few molecules: toward single biomolecule detection, single cell nanoinjections, and remote control of microtubules gliding on kinesin assays.